Well Steve, it's hard to tell from the pic, but you should not have seen it before on other bikes as it is usually corrected early in the finishing process. It will be palpable, as it is a mechanical imperfection...kinda like an edge where the pigment builds due to sag in the paint. Common in tight areas or end of spray patterns like around the seat cluster or bottom bracket. This will not be something that can be sanded out now, as it is beyond that point.
If the thumb screw is not bent, then the dropout is just plain misaligned...no excuse, but sometimes happens.
Paragon sliders use hex head adjustment bolts, very clean and a simple correction short of cutting out the dropouts, refixturing, rebrazing, and new paint. Here's a pic...
Unfortunate errors, but they do occur.
cheers,
rody