Puncture preventative sealant for tubes.

Personally I have given up on them - terribly heavy, so that it's lighter to run a slightly sturdier tyre. Round me it's flints that cause the problem, which tneds to leave a cut not a hole. Rarely did they seal effectively. If your main issue is thorns, then it may be more positive.
 
Depends.
If you buy prefilled tubes, which are usually cheap shit tubes filed with litres of crap sealant, that doesn't work (Basically the stock slime tubes) it's a waste of time.

If you get some nice lightweight tubes and fill with a reasonable amount of decent sealant it's a whole different kettle of spiky thorn things and *can* work well.
 
Re:

Slime tubes have worked very well for years for me, we get hedges trimmed round my way which leaves great big thorns everywhere. I think it's only 50g extra which is nothing really and better than trying to change a tube when it's cold wet and muddy. Haven't had to fix a puncture in about 8 years! But, it can dry out a bit and can clog up the valve - bit of hot water frees it up again, and if you change a tyre it tends not to seal up again in the previous holes. I run tubeless too and would get that finish line stuff when my stans runs out, I'd put that in tubes too - continental presta tubes have removable valve cores as I put slime into my 29er tubes.
 
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